groupment

Psychedelic Drug Effects, Side Effects & Dangers These promising results provide support for more extensive controlled clinical trials of a psychedelic, either LSD or psilocybin, in OCD. The relative lack of efficacy for current therapies argues for more effort to be put into studies of the efficacy of psychedelics for this very-difficult- to-treat condition. Matsushima et al. studied the effect of psilocybin and the dried and powdered mycelium of a psilocybin-containing mushroom Psilocybe argentipes on marble-burying behavior in male mice. P. argentipes at a dose of 0.1–1 g/kg significantly reduced the number of buried marbles without reducing locomotor behavior. In a new study by Schmid et al. , LSD (200 μg) was administered orally to 16 healthy subjects in a double-blind, randomized, placebo-controlled, crossover study. LSD produced a pronounced alteration in waking consciousness that lasted for 12 hours and included visual hallucinations, audio-visual synesthesia, and posit